O. Thompson Mefford
Materials Science and Engineering, Clemson University

Integrated approach for the fabrication of multifunctional metal and metal oxide nanoparticles

Location: EB1 Room 1011

Friday, November 1st 2013 - 11:00 am

Over the past decade there has been extended interest in the use of magnetic nanoparticles for both imaging and therapeutic applications in medicine. Key to the success of these opportunities is the preparation of well-characterized materials with tailored magnetic, thermal, colloidal, and bio-interaction properties. To address these issues we have focused our efforts on three distinct areas in this problem: 1.) Nanoparticle synthesis and morphology, 2.) Surface-ligand interfaces, and 3.) Specialized surface moieties for additional imaging, therapy, and targeting. In addition to these aspects of material design, issues of colloidal stability and magnetic relaxitivity, potential of low cost nano-patterning, and issues related to the environmental transport of these functionalized materials will be discussed.

Dr. Mefford graduate in 2003 with an honors degree in Polymer and Textile Chemistry and minor in Philosophy from Clemson University. He then attended Virginia Tech, where he earned his PhD in Macromolecular Science and Engineering in 2007. For his PhD, he worked on the development of treatments for retinal detachment using hydrophobic ferrofluids. Before returning back to Clemson, Dr. Mefford developed methods for the fabrication and functionalization of microfluidic devices as a Post-doctoral Researcher for The Ohio State University Department of Chemistry. Mefford joined the faculty of the School of Material Science and Engineering at Clemson in the Fall of 2008. His research focuses on developing stable, polymer-iron oxide nanoparticle complexes and composites for biomedical applications. These applications include: developing materials for magnetic hyperthermia, MRI contrast agents, and drug delivery systems. In his free time, Dr. Mefford is found running, cycling, paddling, backpacking, gardening, and homebrewing.

North Carolina State University