Thom LaBean


LaBean earned his BS in biochemistry from the Honors College at Michigan State University, and his PhD in biochemistry from the University of Pennsylvania. He studied protein design as a postdoctoral fellow at Duke University. He then ran his own group as research professor with appointments in the departments of Computer Science, Chemistry, and Biomedical Engineering at Duke. LaBean joined MSE@NCSU in 2011.  Throughout his career, LaBean has studied the structure, evolution, and engineering of biopolymers (biomacromolecules and materials assembled from them). Current research projects involve the design, construction, and testing of self-assembling DNA nanostructures for applications in nanomedicine, molecular materials, and biomimetic fabrication of nanoelectronics.


DNA aerogels and DNA-wrapped CNT aerogels for neuromorphic applications
Hosseini, M., Rahmanian, V., Pirzada, T., Frick, N., Krissanaprasit, A., Khan, S. A., & LaBean, T. H. (2022), MATERIALS TODAY BIO, 16.
Modeling and characterization of stochastic resistive switching in single Ag2S nanowires
Frick, N., Hosseini, M., Guilbaud, D., Gao, M., & LaBean, T. H. (2022), SCIENTIFIC REPORTS, 12(1).
Resistive switching of two-dimensional Ag2S nanowire networks for neuromorphic applications
Hosseini, M., Frick, N., Guilbaud, D., Gao, M., & LaBean, T. H. (2022), JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B, 40(4).
Mechanical and Electrical Properties of DNA Hydrogel-Based Composites Containing Self-Assembled Three-Dimensional Nanocircuits
Gao, M., Krissanaprasit, A., Miles, A., Hsiao, L. C., & LaBean, T. H. (2021), APPLIED SCIENCES-BASEL, 11(5).
Multivalent Aptamer-Functionalized Single-Strand RNA Origami as Effective, Target-Specific Anticoagulants with Corresponding Reversal Agents
Krissanaprasit, A., Key, C. M., Froehlich, K., Pontula, S., Mihalko, E., Dupont, D. M., … LaBean, T. H. (2021, April 21), ADVANCED HEALTHCARE MATERIALS.
Self-Assembling Nucleic Acid Nanostructures Functionalized with Aptamers
Krissanaprasit, A., Key, C. M., Pontula, S., & LaBean, T. H. (2021). [Review of , ]. CHEMICAL REVIEWS, 121(22), 13797–13868.
Genetically Encoded, Functional Single-Strand RNA Origami: Anticoagulant
Krissanaprasit, A., Key, C., Fergione, M., Froehlich, K., Pontula, S., Hart, M., … LaBean, T. H. (2019), ADVANCED MATERIALS, 31(21).
2Precise Coating of a Wide Range of DNA Templates by a Protein Polymer with a DNA Binding Domain
Hernandez-Garcia, A., Estrich, N. A., Werten, M. W. T., Maarel, J. R. C., LaBean, T. H., Wolf, F. A., … Vries, R. (2017), ACS NANO, 11(1), 144–152.
Engineered Diblock Polypeptides Improve DNA and Gold Solubility during Molecular Assembly
Estrich, N. A., Hernandez-Garcia, A., Vries, R., & LaBean, T. H. (2017), ACS NANO, 11(1), 831–842.
Search for effective chemical quenching to arrest molecular assembly and directly monitor DNA nanostructure formation
Majikes, J. M., Nash, J. A., & LaBean, T. H. (2017), NANOSCALE, 9(4), 1637–1644.

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Thom LaBean